Bio-Connect

Anti-osteopontin [hu1A12]

AB00750-1.1-BT
Absolute Antibody
ApplicationsELISA, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application
Product group Antibodies
TargetSPP1
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-osteopontin [hu1A12]
  • Delivery Days Customer
    9
  • Application Supplier Note
    hu1A12 suppreses MDA-MB-435S (highly metastatic human breast cancer cell line) cell migration (evaluated by scratch-wound healing) and also inhibits cell adhesion of MDA-MB-435S cells to human OPN. hu1A12 also inhibits the anti-apoptotic and pro-survival functions of OPN possibly through upregulating Bax, downregulating Bcl-2, and blocking the activation of NF-kappaB. hu1A12 also has been shown to suppress primary breast tumour growth in humans through in vivo studies. This antibody has also been used in ELISA, IHC and SPR studies.
  • Applications
    ELISA, ImmunoHistoChemistry, Neutralisation/Blocking, Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    hu1A12
  • Gene ID6696
  • Target name
    SPP1
  • Target description
    secreted phosphoprotein 1
  • Target synonyms
    BNSP; BSPI; early T-lymphocyte activation 1; ETA-1; nephropontin; OPN; osteopontin; osteopontin/immunoglobulin alpha 1 heavy chain constant region fusion protein; secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1); secreted phosphoprotein 1 variant 6; SPP1/CALPHA1 fusion; urinary stone protein; uropontin
  • Host
    Mouse
  • Isotype
    IgG1
  • Protein IDP10451
  • Protein Name
    Osteopontin
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203