Immunohistochemical staining of formalin fixed and paraffin embedded human kidney tissue section using anti-p120 catenin rabbit monoclonal antibody (Clone RM353) at a 1:5000 dilution.
Immunohistochemical staining of formalin fixed and paraffin embedded human kidney tissue section using anti-p120 catenin rabbit monoclonal antibody (Clone RM353) at a 1:5000 dilution.
anti-p120-catenin (human), Rabbit Monoclonal (RM353)
REV-31-1239-00
ApplicationsWestern Blot, ImmunoHistoChemistry
Product group Antibodies
ReactivityHuman
TargetCTNND1
Overview
- SupplierRevMAb Biosciences
- Product Nameanti-p120-catenin (human), Rabbit Monoclonal (RM353)
- Delivery Days Customer5
- Antibody SpecificityThis antibody reacts human p120 catenin (Catenin delta-1).
- ApplicationsWestern Blot, ImmunoHistoChemistry
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDRM353
- FormulationLiquid
- Gene ID1500
- Target nameCTNND1
- Target descriptioncatenin delta 1
- Target synonymsBCDS2; cadherin-associated Src substrate; CAS; catenin (cadherin-associated protein), delta 1; catenin delta-1; CTNND; p120; p120 catenin; p120(CAS); p120(CTN); P120CAS; P120CTN
- HostRabbit
- IsotypeIgG
- Protein IDO60716
- Protein NameCatenin delta-1
- Scientific DescriptionCatenins are proteins associated with complexes that contain cadherin cell adhesion molecules. p120-Catenin (delta-1-catenin) is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development. It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state. Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins. These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor. p120-Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. - Recombinant Antibody. This antibody reacts human p120 catenin (Catenin delta-1). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. Catenins are proteins associated with complexes that contain cadherin cell adhesion molecules. p120-Catenin (delta-1-catenin) is a member of the p120 Catenin subfamily and is a structural protein involved in neuronal development. It interacts with Actin, Cortactin and Src Kinases to promote neurite elongation or branching, depending upon its phosphorylation state. Like beta-catenin and gamma-catenin, delta-catenins appear to interact with presenilins. These catenin-presenilin interactions can impact cadherin function and regulation of cell-to-cell adhesion. While beta-catenin acts as a transcription regulatory protein in the Wnt/TCF pathway, delta-catenin has been implicated as a regulator of the NF-kB transcription factor. p120-Catenin is an efficient tyrosine kinase substrate implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
- ReactivityHuman
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203