Mouse PIDD is detected in primary MEF cells using anti-PIDD (mouse), mAb (Lise-1) (Prod. N°AG-20B-0038). Method:: Cell extracts from mouse embryo fibroblasts (MEFs) either from WT (A-B) or PIDD KO cells (C-D) were separated by SDS-PAGE under
anti-PIDD (mouse), mAb (Lise-1)
AG-20B-0038
Overview
- SupplierAdipoGen Life Sciences
- Product Nameanti-PIDD (mouse), mAb (Lise-1)
- Delivery Days Customer10
- Antibody SpecificityRecognizes mouse PIDD.
- ApplicationsWestern Blot
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDLise-1
- Concentration1 mg/ml
- Estimated Purity>95%
- FormulationLiquid
- Gene ID57913
- Target namePidd1
- Target descriptionp53 induced death domain protein 1
- Target synonyms1200011D09Rik; AU042446; leucine-rich and death domain containing; leucine-rich repeat and death domain-containing protein; Lr; Lrdd; p53 protein induced, with death domain; p53-induced death domain-containing protein 1; p53-induced protein with a death domain; Pi; Pidd
- HostMouse
- IsotypeIgG2b
- Protein IDQ9ERV7
- Protein Namep53-induced death domain-containing protein 1
- Scientific DescriptionMonoclonal Antibody. Recognizes mouse PIDD. Isotype: Mouse IgG2bkappa. Clone: Lise-1. Applications: WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways. - PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.
- ReactivityMouse
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352203