anti-PIDD, pAb (AL233)

AdipoGen Life Sciences

anti-PIDD, pAb (AL233)

10

Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (Full Length FL-PIDD) and ~50kDa (cleaved protein) by Western blot.

ImmunoPrecipitation, Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Liquid

PIDD1

p53-induced death domain protein 1

leucine-rich repeat and death domain-containing protein; leucine-rich repeats and death domain containing; LRDD; p53-induced death domain-containing protein 1; p53-induced protein with a death domain; PIDD

Rabbit

p53-induced death domain-containing protein 1

PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways. - Polyclonal Antibody. Recognizes human and the native form of mouse PIDD. Detects bands of ~90kDa (full length protein) and ~50kDa (cleaved protein) by Western blot. Source: Rabbit. Applications: IHC, IP, WB. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. PIDD promotes apoptosis downstream of the tumor suppressor as component of the DNA damage/stress response pathway that connects p53/TP53 to apoptosis. It associates with NEMO/IKBKG and RIP1 and enhances sumoylation and ubiquitination of NEMO/IKBKG which is important for activation of the transcription factor NF-kappa-B. It associates with caspase-2 and RAIDD, and induces activation of caspase-2 which is an important regulator in the apoptotic pathways.

Human, Mouse

-20°C,2°C to 8°C

12352203