anti-Podoplanin (human), mAb (18H5)

AdipoGen Life Sciences

anti-Podoplanin (human), mAb (18H5)

10

Recognizes human podoplanin.

Flow Cytometry, Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

18H5

Mouse

IgG1

Monoclonal Antibody. Recognizes human podoplanin. Isotype: Mouse IgG1. Clone: 18H5. Applications: FACS, IHC, WB. Lyophilized. Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth. - Podoplanin is expressed on glomerular epithelial cells (podocytes), type I lung alveolar cells, lymphatic endothelial cells and numerous tumors, including colorectal tumors, squamous cell carcinomas, testicular seminoma and brain tumors. Podoplanin is the ligand for C-type lectin-like receptor 2 (CLEC-2). Their association is dependent on sialic acid on O-glycans of podoplanin. Through its association with CLEC-2, podoplanin induces platelet aggregation and tumor metastasis. Podoplanin is also necessary for lymphatic vessel formation, normal lung cell proliferation and alveolus formation at birth.

Human

2°C to 8°C,-20°C

12352203