Bio-Connect

Anti-prothrombin [POmAb], Human IgG1, kappa

AB04499-10.0-BT
Absolute Antibody
ApplicationsOther Application
Product group Antibodies
ReactivityHuman
TargetF2
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-prothrombin [POmAb], Human IgG1, kappa
  • Delivery Days Customer
    9
  • Antibody Specificity
    The antibody is specific for the open form of prothrombin. Its epitope is located in kringle-1, comprising an extended binding interface centered at residues R90-Y93.
  • Application Supplier Note
    The binding affinity of original format of the antibody to prothrombin was measured by surface plasmon resonance. The crystal structure of the Fab fragment of the antibody was determined. The antibody could prolong phospholipid-initiated and diluted Russell viper venom clotting time (Kumar et al., 2024; PMID: 38437497).
  • Applications
    Other Application
  • Certification
    Research Use Only
  • Clonality
    Monoclonal
  • Clone ID
    POmAb
  • Gene ID2147
  • Target name
    F2
  • Target description
    coagulation factor II, thrombin
  • Target synonyms
    prepro-coagulation factor II; prothrombin; prothrombin B-chain; PT; RPRGL2; THPH1; thrombin factor II
  • Host
    Human
  • Isotype
    IgG1
  • Protein IDP00734
  • Protein Name
    Prothrombin
  • Reactivity
    Human
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203