anti-PSMA (human), Rabbit Monoclonal (RM327)

RevMAb Biosciences

anti-PSMA (human), Rabbit Monoclonal (RM327)

5

This antibody reacts to human PSMA (Prostate-specific membrane antigen).

Western Blot, ImmunoHistoChemistry

Research Use Only

Monoclonal

RM327

Liquid

FOLH1

folate hydrolase 1

cell growth-inhibiting gene 27 protein; FGCP; FOLH; folylpoly-gamma-glutamate carboxypeptidase; GCP2; GCPII; glutamate carboxylase II; glutamate carboxypeptidase 2; glutamate carboxypeptidase II; membrane glutamate carboxypeptidase; mGCP; NAALAD1; NAALADase I; N-acetylated alpha-linked acidic dipeptidase 1; N-acetylated-alpha-linked acidic dipeptidase I; prostate specific membrane antigen variant F; PSM; PSMA; pteroylpoly-gamma-glutamate carboxypeptidase

Rabbit

IgG

Glutamate carboxypeptidase 2

PSMA (Prostate-specific Membrane Antigen) a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer. - Recombinant Antibody. This antibody reacts to human PSMA (Prostate-specific membrane antigen). Applications: WB, IHC. Source: Rabbit. Liquid. 50% Glycerol/PBS with 1% BSA and 0.09% sodium azide. PSMA (Prostate-specific Membrane Antigen) a type II transmembrane glycoprotein belonging to the M28 peptidase family. The protein acts as a glutamate carboxypeptidase on different alternative substrates, including the nutrient folate and the neuropeptide N-acetyl-l-aspartyl-l-glutamate and is expressed in a number of tissues such as prostate, central and peripheral nervous system and kidney. A mutation in this gene may be associated with impaired intestinal absorption of dietary folates, resulting in low blood folate levels and consequent hyperhomocysteinemia. Expression of this protein in the brain may be involved in a number of pathological conditions associated with glutamate excitotoxicity. In the prostate the protein is up-regulated in cancerous cells and is used as an effective diagnostic and prognostic indicator of prostate cancer.

Human

-20°C,2°C to 8°C

12352203