Anti-RANK-L [2G8]

Absolute Antibody

Anti-RANK-L [2G8]

9

The antibody is specific for human-RANK-L. RANKL is a tumor necrosis factor (TNF)-related protein that binds to, and activates, the TNF receptor (TNFR)-related protein Receptor Activator of NF-kB (RANK). RANKL acts as the key cytokine that regulates osteo

The affinity of the original format of the antibody was determined by Scatchard analysis; the results showed that the affinity of the antibody reached 3.2X10E-9. The specificity of the Fab version of the antibody was confirmed by ELISA analysis. The Fab fragment had a good neutralizing effect when tested in an antagonistic RANKL neutralization ability test (WO2009105934A1).

ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

2G8

TNFSF11

TNF superfamily member 11

CD254; hRANKL2; ODF; OPGL; OPTB2; osteoclast differentiation factor; osteoprotegerin ligand; RANKL; receptor activator of nuclear factor kappa B ligand; sOdf; TNF-related activation-induced cytokine; TNLG6B; TRANCE; tumor necrosis factor (ligand) superfamily, member 11; tumor necrosis factor ligand 6B; tumor necrosis factor ligand superfamily member 11; tumor necrosis factor superfamily member 11

Rabbit

IgG

Tumor necrosis factor ligand superfamily member 11

Human

-20°C,2°C to 8°C

12352203