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anti-RANK Receptor antibody

Research Use Only
ARG66061
Arigo Biolaboratories
ApplicationsImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTNFRSF11A
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Overview

  • Supplier
    Arigo Biolaboratories
  • Product Name
    anti-RANK Receptor antibody
  • Delivery Days Customer
    23
  • Applications
    ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID8792
  • Target name
    TNFRSF11A
  • Target description
    TNF receptor superfamily member 11a
  • Target synonyms
    CD265; familial expansile osteolysis; FEO; LOH18CR1; loss of heterozygosity, 18, chromosomal region 1; ODFR; OFE; OPTB7; osteoclast differentiation factor receptor; OSTS; Paget disease of bone 2; PDB2; RANK; receptor activator of NF-KB; receptor activator of nuclear factor-kappa B; TRANCE receptor; TRANCER; TRANCE-R; tumor necrosis factor receptor superfamily member 11A; tumor necrosis factor receptor superfamily, member 11a, NFKB activator
  • Host
    Rabbit
  • Isotype
    IgG
  • Scientific Description
    The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptors can interact with various TRAF family proteins, through which this receptor induces the activation of NF-kappa B and MAPK8/JNK. This receptor and its ligand are important regulators of the interaction between T cells and dendritic cells. This receptor is also an essential mediator for osteoclast and lymph node development. Mutations at this locus have been associated with familial expansile osteolysis, autosomal recessive osteopetrosis, and Paget disease of bone. Alternatively spliced transcript variants have been described for this locus. [provided by RefSeq, Aug 2012]
  • Reactivity
    Human
  • Storage Instruction
    -20°C
  • UNSPSC
    12352203