Anti-SIRP alpha [12G6]

Absolute Antibody

Anti-SIRP alpha [12G6]

9

The binding reactivity of this antibody towards recombinant human SIRPalpha-his fusion protein was checked using ELISA. Flow cytometry was used to detect the binding of the antibody to SIRPalpha on the membrane of human and cynomolgus monkey SIRPalpha overexpressed cells. This antibody binds cynomolgus monkey SIRPalpha with a weaker binding affinity than human SIRPalpha. This antibody can effectively block the binding of CD47 protein to cell surface SIRPalpha (CN110734897).

Flow Cytometry, ELISA, Neutralisation/Blocking

Research Use Only

Monoclonal

12G6

SIRPA

signal regulatory protein alpha

BIT, CD172A, MFR, MYD-1, MYD1, P84, PTPNS1, SHPS1, SIRP, tyrosine-protein phosphatase non-receptor type substrate 1, CD172 antigen-like family member A, brain-immunoglobulin-like molecule with tyrosine-based activation motifs, inhibitory receptor SHPS-1, macrophage fusion receptor, myd-1 antigen, tyrosine phosphatase SHP substrate 1

Human

IgG1

Tyrosine-protein phosphatase non-receptor type substrate 1

This is a reformatted human IgG1 Fc Silent™ antibody, based on the original human IgG2b format, created for improved compatibility with existing reagents, assays and techniques.

Human, Monkey

-20°C,2°C to 8°C

12352203