anti-SLC12A1 / NKCC2 antibody

Arigo Biolaboratories

anti-SLC12A1 / NKCC2 antibody

23

Western Blot, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

Slc12a1

solute carrier family 12 member 1

BSC1; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1; bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; kidney-specific Na-K-Cl symporter; Nkcc2; solute carrier family 12 (sodium/potassium/chloride transporter), member 1; solute carrier family 12 (sodium/potassium/chloride transporters), member 1; solute carrier family 12 member 1; Solute carrier family 12, member 1 (bumetanide-sensitive sodium-[potassium]-chloride cotransporter)

Rabbit

This gene encodes a kidney-specific sodium-potassium-chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henles loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter-like syndromes result from defects in this gene. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their biological validity in humans has not been experimentally proven.[provided by RefSeq, May 2010]

Rat

-20°C

12352203