anti-Syk phospho (Tyr323) antibody

Arigo Biolaboratories

anti-Syk phospho (Tyr323) antibody

23

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

SYK

spleen associated tyrosine kinase

IMD82; p72-Syk; spleen tyrosine kinase; tyrosine-protein kinase SYK

Rabbit

IgG

Phosphorylated

Positive effector of BCR-stimulated responses. Couples the B-cell antigen receptor (BCR) to the mobilization of calcium ion either through a phosphoinositide 3-kinase-dependent pathway, when not phosphorylated on tyrosines of the linker region, or through a phospholipase C-gamma-dependent pathway, when phosphorylated on Tyr-348 and Tyr-352. Thus the differential phosphorylation of Syk can determine the pathway by which BCR is coupled to the regulation of intracellular calcium ion

Human

-20°C

12352203