anti-TAK1 / MAP3K7 antibody

Arigo Biolaboratories

anti-TAK1 / MAP3K7 antibody

23

WB: Recommend incubate at RT for 1h.* The dilutions indicate recommended starting dilutions and the optimal dilutions or concentrations should be determined by the scientist.

Flow Cytometry, Western Blot

Research Use Only

Polyclonal

0.5 mg/ml

Unconjugated

MAP3K7

mitogen-activated protein kinase kinase kinase 7

CSCF, FMD2, MEKK7, TAK1, TGF1a, mitogen-activated protein kinase kinase kinase 7, TGF-beta activated kinase 1, transforming growth factor-beta-activated kinase 1

Goat

IgG

Mitogen-activated protein kinase kinase kinase 7

The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase mediates the signaling transduction induced by TGF beta and morphogenetic protein (BMP), and controls a variety of cell functions including transcription regulation and apoptosis. In response to IL-1, this protein forms a kinase complex including TRAF6, MAP3K7P1/TAB1 and MAP3K7P2/TAB2; this complex is required for the activation of nuclear factor kappa B. This kinase can also activate MAPK8/JNK, MAP2K4/MKK4, and thus plays a role in the cell response to environmental stresses. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

Bovine, Human, Rat

-20°C

41116161