Anti-TLR4 [133-E12], Rabbit IgG-Fc Fusion,

Absolute Antibody

Anti-TLR4 [133-E12], Rabbit IgG-Fc Fusion,

9

The binding specificity of the original version of this antibody (VHH) was tested using ELISA. In a cell-based neutralizing assay with hTLR4-overexpressing HEK cells, an agonistic effect was observed, as measured by increased NFkappaB expression after cell lysis compared to the control group, indicating activation or enhancement of TLR activity instead of neutralization (WO2009138494A2).

ELISA

Research Use Only

Monoclonal

133-E12

TLR4

toll like receptor 4

ARMD10, CD284, TLR-4, TOLL, toll-like receptor 4, hToll, homolog of Drosophila toll, toll like receptor 4 protein

Rabbit

IgG

Toll-like receptor 4

This chimeric rabbit antibody was made using the variable domain sequences of the original Llama VHH format, for improved compatibility with existing reagents, assays and techniques.

Human

-20°C,2°C to 8°C

41116161