Anti-TLR4 [133-E12], Rabbit IgG-Fc Fusion,

Absolute Antibody

Anti-TLR4 [133-E12], Rabbit IgG-Fc Fusion,

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This antibody is specific for human TLR4.

The binding specificity of the original version of this antibody (VHH) was tested using ELISA. In a cell-based neutralizing assay with hTLR4-overexpressing HEK cells, an agonistic effect was observed, as measured by increased NFkappaB expression after cell lysis compared to the control group, indicating activation or enhancement of TLR activity instead of neutralization (WO2009138494A2).

ELISA

Research Use Only

Monoclonal

133-E12

TLR4

toll like receptor 4

ARMD10; CD284; homolog of Drosophila toll; hToll; TLR-4; TOLL; toll like receptor 4 protein; toll-like receptor 4

Rabbit

IgG

Toll-like receptor 4

This is a chimeric antibody, developed from the original camelid VHH antibody, specifically engineered for enhanced compatibility with existing reagents, assays, and techniques.

Human

-20°C,2°C to 8°C

12352203