Bio-Connect

Anti-TNF alpha [CDP 571 (Humicade)]

Ab00448-1.1
Absolute Antibody
ApplicationsELISA, Neutralisation/Blocking
Product group Antibodies
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Overview

  • Supplier
    Absolute Antibody
  • Product Name
    Anti-TNF alpha [CDP 571 (Humicade)]
  • Delivery Days Customer
    7
  • Application Supplier Note
    The antibody binds specifically to TNF-alpha, a pro-inflammatory cytokine which stimulates release of other cytiokines e.g. IL-1, IL-6 and GM-CSF as well as secretion of ICAM-1 and VCAM-1 from endothelial cells. It stimulates acute phase responses and acts as a chemoattractant for NK cells and monocytes/macrophages. The antibody reached Phase II clinical trials with Celltech, UCB.
  • Applications
    ELISA, Neutralisation/Blocking
  • Applications Supplier
    ELISA; NTRL
  • Certification
    Research Use Only
  • Protein IDP01375
  • Protein Name
    Tumor necrosis factor
  • Scientific Description
    NOT FOR THERAPEUTIC USE - This is a research-grade biosimilar. This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
  • Storage Instruction
    -20°C,2°C to 8°C
  • UNSPSC
    12352203