TNF-alpha/TNFSF2, Human
HY-P7058
Protein IDP01375
Product group Proteins / Signaling Molecules
Overview
- SupplierMedChem Express
- Product NameTNF-alpha/TNFSF2, Human
- Delivery Days Customer10
- CertificationResearch Use Only
- Estimated Purity98.0
- Protein IDP01375
- Protein NameTumor necrosis factor
- Scientific DescriptionTumour Necrosis Factor alpha (TNF alpha) is a potent pro-inflammatory cytokine[1]. TNF alpha binds to its receptors, mainly TNFR1 and TNFR2, and then transmits molecular signals for biological functions such as inflammation and cell death[2]. TNF alpha stimulates NF-kappaB pathway via TNFR2 promotes cancer growth, invasion, and metastasis. Anti-TNF-alpha MAb significantly suppresses the tumor development in colitis-associated cancer (CAC) mouse[3]. TNF alpha as a proneurogenic factor activates the SAPK/JNK Pathway and can facilitate neuronal replacement and brain repair in response to brain injury[4]. TNF-alpha/TNFSF2 Protein, Human is a recombinant protein consisting of 157 amino acids (V77-L233) and is produced in E. coli.
- Storage Instruction-20°C
- UNSPSC12352202
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