anti-TRAIL-R2 (human), mAb (TR2.21)

AdipoGen Life Sciences

anti-TRAIL-R2 (human), mAb (TR2.21)

10

Flow Cytometry, ImmunoHistoChemistry

Research Use Only

Monoclonal

TR2.21

1 mg/ml

>95%

TNFRSF10B

TNF receptor superfamily member 10b

CD262, DR5, KILLER, KILLER/DR5, TRAIL-R2, TRAILR2, TRICK2, TRICK2A, TRICK2B, TRICKB, ZTNFR9, tumor necrosis factor receptor superfamily member 10B, Fas-like protein, TNF-related apoptosis-inducing ligand receptor 2, apoptosis inducing protein TRICK2A/2B, apoptosis inducing receptor TRAIL-R2, cytotoxic TRAIL receptor-2, death domain containing receptor for TRAIL/Apo-2L, death receptor 5, p53-regulated DNA damage-inducible cell death receptor(killer), tumor necrosis factor receptor superfamily, member 10b, tumor necrosis factor receptor-like protein ZTNFR9

Mouse

IgG1

Tumor necrosis factor receptor superfamily member 10B

Monoclonal Antibody. Recognizes human TRAIL-R2. Does not cross-react with human TRAIL-R1, -R3 or -R4. Isotype: Mouse IgG1. Clone: TR2.21. Applications: FACS, IHC. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB. - TRAIL-R2 is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

-20°C,2°C to 8°C

12352203