anti-TRB-3 (human), pAb

AdipoGen Life Sciences

anti-TRB-3 (human), pAb

10

Western Blot, ELISA, ImmunoHistoChemistry

Research Use Only

Polyclonal

1 mg/ml

TRIB3

tribbles pseudokinase 3

C20orf97; neuronal cell death inducible putative kinase; NIPK; p65-interacting inhibitor of NF-kappaB; p65-interacting inhibitor of NF-kappa-B; SINK; SKIP3; TRB3; TRB-3; tribbles homolog 3

Rabbit

Tribbles homolog 3

Polyclonal Antibody. Recognizes human TRB-3. Detects a band of ~28kDa by Western blot (predicted 39kDa). Source: Rabbit. Applications: ELISA, IHC, WB. Liquid. 0.2microm-filtered solution in PBS, pH 7.4. Contains no preservatives. Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells. - Tribbles homolog 3 (TRB-3) is a pseudokinase, shown to act as a potent negative regulator of PPARgamma, a master regulator of adipocyte differentiation, and to control adipogenesis. It disrupts insulin signaling by binding directly to Akt kinases and blocking their activation. It interacts also with the NF-kappaB transactivator p65 RELA. May play a role in programmed neuronal cell death but does not appear to affect non-neuronal cells.

-20°C,2°C to 8°C

12352203