Bio-Connect

TRIB3 antibody [N3C3]

GTX113991
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetTRIB3
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Overview

  • Supplier
    GeneTex
  • Product Name
    TRIB3 antibody [N3C3]
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID57761
  • Target name
    TRIB3
  • Target description
    tribbles pseudokinase 3
  • Target synonyms
    C20orf97; neuronal cell death inducible putative kinase; NIPK; p65-interacting inhibitor of NF-kappaB; p65-interacting inhibitor of NF-kappa-B; SINK; SKIP3; TRB3; TRB-3; tribbles homolog 3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDQ96RU7
  • Protein Name
    Tribbles homolog 3
  • Scientific Description
    The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. [provided by RefSeq]
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Endoplasmic reticulum-targeting photosensitizer Hypericin confers chemo-sensitization towards oxaliplatin through inducing pro-death autophagy. Lin S et al., 2017 Jun, Int J Biochem Cell Biol
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  • EZH2 inhibitors transcriptionally upregulate cytotoxic autophagy and cytoprotective unfolded protein response in human colorectal cancer cells. Hsieh YY et al., 2016, Am J Cancer Res
    Read more