anti-Ubiquitin antibody [Ubi-1]
ARG11151
ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityBovine, Chicken
TargetUBB
Overview
- SupplierArigo Biolaboratories
- Product Nameanti-Ubiquitin antibody [Ubi-1]
- Delivery Days Customer23
- ApplicationsWestern Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone IDUbi-1
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID281370
- Target nameUBB
- Target descriptionubiquitin B
- Target synonymspolyubiquitin; polyubiquitin-B
- HostMouse
- IsotypeIgG1
- Scientific DescriptionThis gene encodes ubiquitin, one of the most conserved proteins known. Ubiquitin has a major role in targeting cellular proteins for degradation by the 26S proteosome. It is also involved in the maintenance of chromatin structure, the regulation of gene expression, and the stress response. Ubiquitin is synthesized as a precursor protein consisting of either polyubiquitin chains or a single ubiquitin moiety fused to an unrelated protein. This gene consists of three direct repeats of the ubiquitin coding sequence with no spacer sequence. Consequently, the protein is expressed as a polyubiquitin precursor with a final amino acid after the last repeat. An aberrant form of this protein has been detected in patients with Alzheimers disease and Down syndrome. Pseudogenes of this gene are located on chromosomes 1, 2, 13, and 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
- ReactivityBovine, Chicken
- Storage Instruction-20°C
- UNSPSC12352203