Anti-ZHX2 Antibody

HUABIO

Anti-ZHX2 Antibody

7

Western Blot, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin

WB,IHC-P

Research Use Only

Polyclonal

1 mg/ml

Unconjugated

ZHX2

zinc fingers and homeoboxes 2

AFR1, RAF, zinc fingers and homeoboxes protein 2, AFP regulator 1, alpha-fetoprotein regulator 1, regulator of AFP, transcription factor ZHX2, zinc finger and homeodomain protein 2

Rabbit

IgG

Zinc fingers and homeoboxes protein 2

Zinc fingers and homeoboxes protein 2 is a protein that in humans is encoded by the ZHX2 gene. The members of the zinc fingers and homeoboxes gene family are nuclear homodimeric transcriptional repressors that interact with the A subunit of nuclear factor-Y (NF-YA) and contain two C2H2-type zinc fingers and five homeobox DNA-binding domains. This gene encodes member 2 of this gene family. In addition to forming homodimers, this protein heterodimerizes with member 1 of the zinc fingers and homeoboxes family. Represses the promoter activity of the CDC25C gene stimulated by NFYA. May play a role in retinal development where it regulates the composition of bipolar cell populations, by promoting differentiation of bipolar OFF-type cells (By similarity). In the brain, may promote maintenance and suppress differentiation of neural progenitor cells in the developing cortex (By similarity).

Human

Human

-20°C,2°C to 8°C

41116161