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Apcin [300815-04-7]

Apcin [300815-04-7]

T8561
TargetMol Chemicals
CAS Number300815-04-7
DownloadMSDS
Product group Chemicals
Estimated Purity96.74%
Molecular Weight438.65
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Apcin [300815-04-7]
  • Delivery Days Customer
    4
  • CAS Number
    300815-04-7
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Apcin
  • Estimated Purity
    96.74%
  • Molecular Formula
    C13H14Cl3N7O4
  • Molecular Weight
    438.65
  • Scientific Description
    Apcin is a potent and competitive inhibitor of anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. It acts by blocking mitotic exit and being synergistically amplified by co-addition of Ts-Arg-OMe.
  • Shelf life instruction
    3 years
  • SMILES
    Cc1ncc(n1CCC(=O)NC(Nc1ccccc1)C(Cl)(Cl)Cl)[N+]([O-])=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

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