APE1 antibody [13B8E5C2]

GeneTex

APE1 antibody [13B8E5C2]

9

WB: 1:100 - 1:2000. ICC/IF: 1:50 - 1:200. IHC-P: 1:100. IHC-Fr: 1:10 - 1:500. IP: 1:10 - 1:500. ChIP assay: 1:10 - 1:500. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Gel Shift Assay, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ChIP Chromatin ImmunoPrecipitation, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin, Other Application

Research Use Only

Monoclonal

13B8E5C2

1 mg/ml

Unconjugated

APEX1

apurinic/apyrimidinic endodeoxyribonuclease 1

APE, APE1, APEN, APEX, APX, HAP1, REF1, DNA repair nuclease/redox regulator APEX1, AP endonuclease class I, AP lyase, APEX nuclease (multifunctional DNA repair enzyme) 1, DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, apurinic-apyrimidinic endonuclease 1, apurinic/apyrimidinic (abasic) endonuclease, deoxyribonuclease (apurinic or apyrimidinic), protein REF-1, redox factor-1

Mouse

IgG2b

DNA-(apurinic or apyrimidinic site) lyase

Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5 to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq]

-20°C or -80°C,2°C to 8°C

12352203