ELISA analysis of antigen using GTX60446 Apolipoprotein E antibody [1H4]. Red : Control antigen 100ng Purple : Antigen 10ng Green : Antigen 50ng Blue : Antigen 100ng
![FACS analysis of HepG2 cells using GTX60446 Apolipoprotein E antibody [1H4]. Green : Apolipoprotein E Purple : negative control](https://www.genetex.com/upload/website/prouct_img/normal/GTX60446/GTX60446_20170912_FACS_w_23061123_124.webp "FACS analysis of HepG2 cells using GTX60446 Apolipoprotein E antibody [1H4]. Green : Apolipoprotein E Purple : negative control")
![IHC-P analysis of liver cancer tissue (left) and brain tissue (right) using GTX60446 Apolipoprotein E antibody [1H4].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60446/GTX60446_20170912_IHC-P_w_23061123_574.webp "IHC-P analysis of liver cancer tissue (left) and brain tissue (right) using GTX60446 Apolipoprotein E antibody [1H4].")
![WB analysis of HEK293 (1) and ApoE (AA: 20-267)-hIgGFc transfected HEK293 (2) cell lysate using GTX60446 Apolipoprotein E antibody [1H4].](https://www.genetex.com/upload/website/prouct_img/normal/GTX60446/GTX60446_20170912_WB_w_23061123_965.webp "WB analysis of HEK293 (1) and ApoE (AA: 20-267)-hIgGFc transfected HEK293 (2) cell lysate using GTX60446 Apolipoprotein E antibody [1H4].")
ELISA analysis of antigen using GTX60446 Apolipoprotein E antibody [1H4]. Red : Control antigen 100ng Purple : Antigen 10ng Green : Antigen 50ng Blue : Antigen 100ng
Apolipoprotein E antibody [1H4]
GTX60446
ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman
TargetAPOE
Overview
- SupplierGeneTex
- Product NameApolipoprotein E antibody [1H4]
- Delivery Days Customer9
- Application Supplier NoteWB: 1/500 - 1/2000. IHC-P: 1/200 - 1/1000. FACS: 1/200 - 1/400. ELISA: 1/10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsFlow Cytometry, Western Blot, ELISA, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityMonoclonal
- Clone ID1H4
- ConjugateUnconjugated
- Gene ID348
- Target nameAPOE
- Target descriptionapolipoprotein E
- Target synonymsAD2; APO-E; ApoE4; apolipoprotein E; apolipoprotein E3; LDLCQ5; LPG
- HostMouse
- IsotypeIgG1
- Protein IDP02649
- Protein NameApolipoprotein E
- Scientific DescriptionThe protein encoded by this gene is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. This gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in this gene result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
- ReactivityHuman
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Glycogen synthase kinase 3beta inhibitors prevent hepatitis C virus release/assembly through perturbation of lipid metabolism. Sarhan MA et al., 2017 May 31, Sci RepRead more