APOO Antibody, FITC conjugated

Cusabio

APOO Antibody, FITC conjugated

20

Research Use Only

Polyclonal

FITC

APOO

apolipoprotein O

FAM121B, MIC26, MICOS26, Mic23, My025, MICOS complex subunit MIC26, MICOS complex subunit MIC23, brain my025, family with sequence similarity 121B, mitochondrial contact site and cristae organizing system subunit 26

Rabbit

IgG

MICOS complex subunit MIC26

Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane. Plays a crucial role in crista junction formation and mitochondrial function (PubMed:25764979). Can promote cardiac lipotoxicity by enhancing mitochondrial respiration and fatty acid metabolism in cardiac myoblasts (PubMed:24743151). Promotes cholesterol efflux from macrophage cells. Detected in HDL, LDL and VLDL. Secreted by a microsomal triglyceride transfer protein (MTTP)-dependent mechanism, probably as a VLDL-associated protein that is subsequently transferred to HDL (PubMed:16956892).

Human

-20°C or -80°C

41116161