APP antibody
GTX112677
ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
TargetAPP
Overview
- SupplierGeneTex
- Product NameAPP antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.46 mg/ml
- ConjugateUnconjugated
- Gene ID351
- Target nameAPP
- Target descriptionamyloid beta precursor protein
- Target synonymsAAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4, amyloid-beta precursor protein, alzheimer disease amyloid A4 protein homolog, alzheimer disease amyloid protein, amyloid beta (A4) precursor protein, amyloid beta A4 protein, amyloid precursor protein, beta-amyloid peptide, beta-amyloid peptide(1-40), beta-amyloid peptide(1-42), beta-amyloid precursor protein, cerebral vascular amyloid peptide, peptidase nexin-II, protease nexin-II, testicular tissue protein Li 2
- HostRabbit
- IsotypeIgG
- Protein IDP05067
- Protein NameAmyloid-beta A4 protein
- Scientific DescriptionThis gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
![IHC-P analysis of human amyloidosis tissue using GTX27501 beta Amyloid (1-40) antibody [BAM-10].](https://www.genetex.com/upload/website/prouct_img/normal/GTX27501/GTX27501_20230724_IHC-P_23072402_220.webp)



![ICC/IF analysis of COS7 cells transiently transfected with APP plasmid using GTX84873 APP antibody [4C3].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84873/GTX84873_1270_ICCIF_w_23061420_163.webp)
![ICC/IF analysis of HeLa cells using GTX84877 APP antibody [2B10].](https://www.genetex.com/upload/website/prouct_img/normal/GTX84877/GTX84877_1271_ICCIF_w_23061420_347.webp)