Apremilast [608141-41-9]

MedChem Express

Apremilast [608141-41-9]

10

608141-41-9

Research Use Only

99.91

C22H24N2O7S

460.50

Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-alpha release by lipopolysaccharide (LPS) with an IC50 of 104 nM[1].

CC(NC1=CC=CC(C(N2[C@@H](C3=CC=C(OC)C(OCC)=C3)CS(=O)(C)=O)=O)=C1C2=O)=O

-20°C,2°C to 8°C

12352200