Apremilast [608141-41-9]

AbMole BioScience

Apremilast [608141-41-9]

7

608141-41-9

Research Use Only

99.52%

C22H24N2O7S

460.5

Apremilast is a novel, orally available small molecule inhibitor of PDE4 with IC50 of 74 nM. Apremilast inhibits TNF-alfa release by lipopolysaccharide (LPS) with an IC50 of 104 nM.

CCOC1=C(OC)C=CC(=C1)C(C[S](C)(=O)=O)N2C(=O)C3=C(C2=O)C(=CC=C3)NC(C)=O

-20°C

12161500