ICC/IF analysis of methanol-fixed, ARAP1-transfected NCTC cells treated with TRAIL for 0, 30 or 60 using GTX80235 ARAP1 antibody [ARAP1-2]. Arrowheads show ARAP1-DR4 colocalization at the plasma membrane and intracellular membranes, whereas arrows show their colocalization in early endosomes. Red : DR4 Green : GTX80235
ICC/IF analysis of methanol-fixed, ARAP1-transfected NCTC cells treated with TRAIL for 0, 30 or 60 using GTX80235 ARAP1 antibody [ARAP1-2]. Arrowheads show ARAP1-DR4 colocalization at the plasma membrane and intracellular membranes, whereas arrows show their colocalization in early endosomes. Red : DR4 Green : GTX80235
ARAP1 antibody [ARAP1-2]
GTX80235
Overview
- SupplierGeneTex
- Product NameARAP1 antibody [ARAP1-2] - Orthogonal Validated
- Delivery Days Customer9
- Antibody SpecificityThis antibody reacts with C-terminal part of ARAP1, a 160 kDa adaptor protein.
- Clone IDARAP1-2
- Concentration1 mg/ml
- FormulationLiquid
- Gene ID116985
- Target nameARAP1
- Target descriptionArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
- Target synonymsarf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1; ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1; centaurin-delta-2; CENTD2; cnt-d2
- Protein IDQ96P48
- Protein NameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
- Scientific DescriptionThe protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- Storage Instruction2°C to 8°C
- UNSPSC12352203