ARAP1 antibody, C-term
GTX25912
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
Product group Antibodies
TargetARAP1
Overview
- SupplierGeneTex
- Product NameARAP1 antibody, C-term
- Delivery Days Customer7
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration0.50 mg/ml
- ConjugateUnconjugated
- Gene ID116985
- Target nameARAP1
- Target descriptionArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
- Target synonymsCENTD2, cnt-d2, arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1, ARF-GAP, RHO-GAP, ankyrin repeat, and pleckstrin homology domains-containing protein 1, centaurin-delta-2
- HostGoat
- IsotypeIgG
- Protein IDQ96P48
- Protein NameArf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 1
- Scientific DescriptionThe protein encoded by this gene contains SAM, ARF-GAP, RHO-GAP, ankyrin repeat, RAS-associating, and pleckstrin homology (PH) domains. In vitro, this protein displays RHO-GAP and phosphatidylinositol (3,4,5) trisphosphate (PIP3)-dependent ARF-GAP activity. The encoded protein associates with the Golgi, and the ARF-GAP activity mediates changes in the Golgi and the formation of filopodia. It is thought to regulate the cell-specific trafficking of a receptor protein involved in apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008]
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203

![ICC/IF analysis of methanol-fixed, ARAP1-transfected NCTC cells treated with TRAIL for 0, 30 or 60 using GTX80235 ARAP1 antibody [ARAP1-2]. Arrowheads show ARAP1-DR4 colocalization at the plasma membrane and intracellular membranes, whereas arrows show their colocalization in early endosomes. Red : DR4 Green : GTX80235](https://www.genetex.com/upload/website/prouct_img/normal/GTX80235/GTX80235_20191028_ICC-IF_1_w_23061322_886.webp)




