Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ARC Polyclonal Antibody at dilution 1:50
Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ARC Polyclonal Antibody at dilution 1:50
ARC Polyclonal Antibody
E-AB-10826
Product group Antibodies
Overview
- SupplierElabscience
- Product NameARC Polyclonal Antibody
- Delivery Days Customer12
- Applications SupplierELISA IHC
- CertificationResearch Use Only
- Concentration0.5mg/ml
- Scientific DescriptionArc (for activity-regulated cytoskeleton-associated protein) is a growth factor and immediate early gene that is enriched in brain. Arc mRNA and protein levels are induced by neuronal activity, which is necessary to stimulate neuroplasticity, indicating a potential role for Arc in activity-dependent changes in dendrite function. Arc expression has been detected in neuronal cell bodies and dendrites in the hippocampus, amygdala, hypothalamus, striatum and cortex. Arc has been shown to localize to the cytoskeleton of neuronal cells and appears to colocalize with F-Actin, although it may associate with an Actin-associated protein rather than directly with F-Actin. It has been shown that cocaine-stimulated neuronal activity results in increased Arc mRNA levels in striatum.
- UNSPSC12352203