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Arginase 1 antibody

Research Use Only
GTX109242
GeneTex
ApplicationsFlow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetARG1
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Overview

  • Supplier
    GeneTex
  • Product Name
    Arginase 1 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IHC-Fr: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:1000. ELISA: 1:1000-1:10000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    Flow Cytometry, ImmunoFluorescence, ImmunoPrecipitation, Western Blot, ELISA, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Frozen, ImmunoHistoChemistry Paraffin
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    0.72 mg/ml
  • Conjugate
    Unconjugated
  • Formulation
    Liquid
  • Gene ID383
  • Target name
    ARG1
  • Target description
    arginase 1
  • Target synonyms
    arginase, liver; arginase-1; liver-type arginase; type I arginase
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP05089
  • Protein Name
    Arginase-1
  • Scientific Description
    Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. [provided by RefSeq]
  • Reactivity
    Human, Mouse, Rat
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • Multi-Hit White Matter Injury-Induced Cerebral Palsy Model Established by Perinatal Lipopolysaccharide Injection. Liu L et al., 2022, Front Pediatr
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  • Grafted human ESC-derived astroglia repair spinal cord injury via activation of host anti-inflammatory microglia in the lesion area. Wang J et al., 2022, Theranostics
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  • Immunosuppressive Features of the Microenvironment in Lymph Nodes Granulomas from Tuberculosis and HIV-Co-Infected Patients. Ashenafi S et al., 2022 Apr, Am J Pathol
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  • FcgammaRIIB potentiates differentiation of myeloid-derived suppressor cells to mediate tumor immunoescape. Wu L et al., 2022, Theranostics
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  • Panobinostat enhances olaparib efficacy by modifying expression of homologous recombination repair and immune transcripts in ovarian cancer. Wilson AJ et al., 2022 Feb, Neoplasia
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  • Cryptotanshinone ameliorates CUS-induced depressive-like behaviors in mice. Wang K et al., 2021 Jan 1, Transl Neurosci
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  • Potent but transient immunosuppression of T-cells is a general feature of CD71(+) erythroid cells. Grzywa TM et al., 2021 Dec 10, Commun Biol
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  • The MEMIC is an ex vivo system to model the complexity of the tumor microenvironment. Janska L et al., 2021 Aug 1, Dis Model Mech
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  • Sevoflurane preconditioning protects experimental ischemic stroke by enhancing anti-inflammatory microglia/macrophages phenotype polarization through GSK-3beta/Nrf2 pathway. Cai M et al., 2021 Nov, CNS Neurosci Ther
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  • Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia. Vilhena ER et al., 2021 Sep 1, Behav Pharmacol
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