ARHGEF18 antibody
GTX102223
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
Product group Antibodies
ReactivityHuman, Mouse, Rat
TargetARHGEF18
Overview
- SupplierGeneTex
- Product NameARHGEF18 antibody
- Delivery Days Customer9
- Application Supplier NoteWB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
- ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry, ImmunoHistoChemistry, ImmunoHistoChemistry Paraffin
- CertificationResearch Use Only
- ClonalityPolyclonal
- Concentration1 mg/ml
- ConjugateUnconjugated
- Gene ID23370
- Target nameARHGEF18
- Target descriptionRho/Rac guanine nucleotide exchange factor 18
- Target synonyms114 kDa Rho-specific guanine nucleotide exchange factor; p114RhoGEF; P114-RhoGEF; rho guanine nucleotide exchange factor 18; Rho/Rac guanine nucleotide exchange factor (GEF) 18; Rho-specific guanine nucleotide exchange factor p114; RP78; SA-RhoGEF; septin-associated RhoGEF
- HostRabbit
- IsotypeIgG
- Protein IDQ6ZSZ5
- Protein NameRho guanine nucleotide exchange factor 18
- Scientific DescriptionRho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq]
- ReactivityHuman, Mouse, Rat
- Storage Instruction-20°C or -80°C,2°C to 8°C
- UNSPSC12352203
References
- Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly. Haas AJ et al., 2020 Jul 21, Cell RepRead more
- Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs. Lu A et al., 2018 Dec 17, ElifeRead more
- The exon 38-containing ARHGEF11 splice isoform is differentially expressed and is required for migration and growth in invasive breast cancer cells. Itoh M et al., 2017 Nov 3, OncotargetRead more
- An apical MRCK-driven morphogenetic pathway controls epithelial polarity. Zihni C et al., 2017 Sep, Nat Cell BiolRead more
- CRB3A Controls the Morphology and Cohesion of Cancer Cells through Ehm2/p114RhoGEF-Dependent Signaling. Loie E et al., 2015 Oct, Mol Cell BiolRead more
- MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. Yamamura S et al., 2012, PLoS OneRead more
- MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. Yamamura S et al., 2012 Feb, CarcinogenesisRead more
- Lulu2 regulates the circumferential actomyosin tensile system in epithelial cells through p114RhoGEF. Nakajima H et al., 2011 Oct 17, J Cell BiolRead more