Western blot analysis of extracts of various cell lines using ARNT2 Polyclonal Antibody at 1:1000 dilution.
Western blot analysis of extracts of various cell lines using ARNT2 Polyclonal Antibody at 1:1000 dilution.
ARNT2 Polyclonal Antibody
E-AB-62325
Product group Antibodies
Overview
- SupplierElabscience
- Product NameARNT2 Polyclonal Antibody
- Delivery Days Customer12
- CertificationResearch Use Only
- Scientific DescriptionThis gene encodes a member of the basic-helix-loop-helix-Per-Arnt-Sim (bHLH-PAS) superfamily of transcription factors. The encoded protein acts as a partner for several sensor proteins of the bHLH-PAS family, forming heterodimers with the sensor proteins that bind regulatory DNA sequences in genes responsive to developmental and environmental stimuli. Under hypoxic conditions, the encoded protein complexes with hypoxia-inducible factor 1alpha in the nucleus and this complex binds to hypoxia-responsive elements in enhancers and promoters of oxygen-responsive genes. A highly similar protein in mouse forms functional complexes with both aryl hydrocarbon receptors and Single-minded proteins, suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis, respectively.
- UNSPSC12352203