Artemis antibody [HL1227]

GeneTex

Artemis antibody [HL1227]

9

WB: 1:500-1:3000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

ImmunoFluorescence, Western Blot, ImmunoCytoChemistry

Research Use Only

Monoclonal

HL1227

1 mg/ml

Unconjugated

DCLRE1C

DNA cross-link repair 1C

A-SCID; DCLREC1C; DNA cross-link repair 1C (PSO2 homolog, S. cerevisiae); protein artemis; RS-SCID; SCIDA; severe combined immunodeficiency, type a (Athabascan); SNM1 homolog C; SNM1C; SNM1-like protein

Rabbit

IgG

Protein artemis

This gene encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single-strand-specific 5-3 exonuclease activity; it also exhibits endonuclease activity on 5 and 3 overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in this gene can cause Athabascan-type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

Human

-20°C or -80°C,2°C to 8°C

12352203