Artemisinin [63968-64-9]

Name: Artemisinin [63968-64-9]
SKU: AG-CN2-0467_A27
Availability: BackOrder

AG-CN2-0467

CAS Number63968-64-9

Product group Chemicals

Estimated Purity>98%

Molecular Weight282.3

Overview

Supplier
AdipoGen Life Sciences
Product Name
Artemisinin
Delivery Days Customer
10
CAS Number
63968-64-9
Certification
Research Use Only
Estimated Purity
>98%
Molecular Formula
C15H22O5
Molecular Weight
282.3
Scientific Description
Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Functional ARX inhibitor. Enhancer of GABAA signaling. Shown to promote the in vivo conversion of pancreatic alpha cells into functional beta-like cells through enhanced GABA signaling and may have potential as a therapeutic for diabetes. Targets Gephyrin. - Chemical. CAS: 63968-64-9. Formula: C15H22O5. MW: 282.3. Isolated from Artemisia annua. Anti-malaria. Apoptosis inducer. Anti-cancer. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO).
SMILES
[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@]4(C)OO[C@@]13[C@]([H])(OC(=O)[C@@H]2C)O4
Storage Instruction
-20°C,2°C to 8°C
UNSPSC
12352200

Qinghaosu (artemisinin): an antimalarial drug from China: D.L. Klayman; Science 228, 1049 (1985)
The development of the antimalarial drugs with new type of chemical structure--qinghaosu and dihydroqinghaosu: Y. Tu; SE Asian J. Trop. Med. Publ. Health 35, 250 (2004)
Artemisinin induces apoptosis in human cancer cells: N.P. Singh & H.C. Lai; Anticancer Res. 24, 2277 (2004)
Artemisinin attenuates lipopolysaccharide-stimulated proinflammatory responses by inhibiting NF-kappaB pathway in microglia cells: C. Zhu, et al.; PLoS One 7, e35125 (2012)
Differential effect of artemisinin against cancer cell lines: M. Tilaoui, et al.; Nat. Prod. Bioprospect. 4, 189 (2014)