
Chemical Structure
Artesunate [88495-63-0]

AG-CN2-0469
Overview
- SupplierAdipoGen Life Sciences
- Product NameArtesunate
- Delivery Days Customer10
- CAS Number88495-63-0
- CertificationResearch Use Only
- Estimated Purity>98%
- Molecular FormulaC19H28O8
- Molecular Weight384.4
- Scientific DescriptionChemical. CAS: 88495-63-0. Formula: C19H28O8. MW: 384.4. Semi-synthetic derivative of artemisinin originally isolated from Artemisia annua. Semi-synthetic derivative of artemisinin. Anti-malaria. Anti-schistosomiasis. Inhibitor of human cytomegalovirus (CMV). Apoptosis inducer. Anti-cancer. Immunosuppressant. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). - Semi-synthetic derivative of artemisinin. Anti-malaria. Anti-schistosomiasis. Inhibitor of human cytomegalovirus (CMV). Apoptosis inducer. Anti-cancer. Immunosuppressant. Inhibits production of tumor necrosis factor-alpha (TNF-alpha), interleukin-6 (IL-6), monocyte chemotactic protein-1 (MCP-1) and nitric oxide (NO). Functional ARX inhibitor. Enhancer of GABAA signalling. Targets Gephyrin. Inducer of glucose-6-phosphate dehydrogenase (G6PDH) activity (25fold), the rate limiting enzyme of the pentose phosphate pathway (PPP). Sown to have anti-SARS-CoV-2 activity with an EC50 of 12.98 +/- 5.30microM, and beeing potentially useful in the treatment of COVID-19.
- SMILES[H][C@@]12CC[C@@H](C)[C@]3([H])CC[C@]4(C)OO[C@@]13[C@]([H])(O[C@@H](OC(=O)CCC(O)=O)[C@@H]2C)O4
- Storage Instruction-20°C,2°C to 8°C
- UNSPSC12352200