AS2863619 [2241300-51-4]

TargetMol Chemicals

AS2863619 [2241300-51-4]

9

2241300-51-4

Chemical

Research Use Only

AS2863619

C16H14Cl2N8O

405.24

AS2863619 is an oral inhibitor of cyclin-dependent kinase 8 (CDK8) and CDK19. Inhibition of CDK8/19 can enhance the activation of STAT5, thereby activating the Foxp3 gene. It can convert antigen-specific effector/memory T cells into Foxp3+ regulatory T cells to study various immune diseases.

3 years

Cl.Cl.Cc1nc2ccc(cc2[nH]1)-n1c(nc2cnccc12)-c1nonc1N

-20°C

12352200