ASIP Antibody, HRP conjugated

Cusabio

ASIP Antibody, HRP conjugated

20

ELISA

Research Use Only

Polyclonal

HRP

ASIP

agouti signaling protein

AGSW, AGTI, AGTIL, ASP, SHEP9, agouti-signaling protein, agouti signaling protein, nonagouti homolog, agouti switch protein, nonagouti homolog

Rabbit

IgG

Agouti-signaling protein

Involved in the regulation of melanogenesis. The binding of ASP to MC1R precludes alpha-MSH initiated signaling and thus blocks production of cAMP, leading to a down-regulation of eumelanogenesis (brown/black pigment) and thus increasing synthesis of pheomelanin (yellow/red pigment). In higher primates, agouti may affect the quality of hair pigmentation rather than its pattern of deposition. Could well play a role in neuroendocrine aspects of melanocortin action. May have some functional role in regulating the lipid metabolism with adipocytes.

Human

-20°C or -80°C

41116161