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ASP2453

HY-132966
MedChem Express
CAS Number2241719-73-1
DownloadMSDS
Product group Chemicals
Estimated Purity98.28
Molecular Weight747.85
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Overview

  • Supplier
    MedChem Express
  • Product Name
    ASP2453 [2241719-73-1]
  • Delivery Days Customer
    5
  • CAS Number
    2241719-73-1
  • Certification
    Research Use Only
  • Estimated Purity
    98.28
  • Molecular Formula
    C40H48F3N7O4
  • Molecular Weight
    747.85
  • Scientific Description
    ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC 50 value of 40 nM.
  • SMILES
    C=CC(N1CC2(CCN(C3=C4C=C(C5CC5)C(C6=C(C)C=CC7=C6C=NN7)=C(OCC(F)(F)F)C4=NC(OC8CCN(CCCOC)CC8)=N3)CC2)C1)=O
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200