More than 130 suppliers
ISO certified
In-house tech support
we Connect you
Bio-Connect
ProductsBack/ASP2453 [2241719-73-1]
ASP2453 [2241719-73-1]

ASP2453 [2241719-73-1]

T39738
TargetMol Chemicals
CAS Number2241719-73-1
DownloadMSDS
Product group Chemicals
Estimated Purity0.9657
Molecular Weight747.85
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request
More than 130 suppliers
ISO certified
In-house tech support

Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    ASP2453 [2241719-73-1]
  • Delivery Days Customer
    9
  • CAS Number
    2241719-73-1
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    ASP2453
  • Estimated Purity
    0.9657
  • Molecular Formula
    C40H48F3N7O4
  • Molecular Weight
    747.85
  • Scientific Description
    ASP2453 is a potent, selective, and covalent inhibitor of KRAS G12C that inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM.
  • Shelf life instruction
    3 years
  • SMILES
    COCCCN1CCC(CC1)Oc1nc(N2CCC3(CN(C3)C(=O)C=C)CC2)c2cc(C3CC3)c(c(OCC(F)(F)F)c2n1)-c1c(C)ccc2[nH]ncc12
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200

References

  • Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models. Nakayama A et al., 2022 Mar, Br J Cancer
    Read more

Related products

Product group Chemicals
Biorbyt
ASP2453ORB1303490
CAS Number2241719-73-1
Estimated Purity96.57%
Molecular Weight747.85
  • SizePrice
Product group Chemicals
MedChem Express
ASP2453HY-132966
CAS Number2241719-73-1
Estimated Purity98.28
Molecular Weight747.85
  • SizePrice