ASP3026

MedChem Express

ASP3026 [1097917-15-1]

10

1097917-15-1

Research Use Only

99.88

C29H40N8O3S

580.74

ASP3026 is a selective and orally active inhibitor of anaplastic lymphoma kinase ( ALK ). ASP3026 is a selective and oral active anaplastic lymphoma kinase ( ALK ) inhibitor with a IC 50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R , STAT3 , AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP . It also inhibited ROS and ACK . ASP3026 can be used in anti-tumor research [1] [2] [3] [4] .

COC(C=C(N1CCC(N2CCN(C)CC2)CC1)C=C3)=C3NC4=NC=NC(NC5=C(S(C(C)C)(=O)=O)C=CC=C5)=N4

-20°C,2°C to 8°C

12352200