ASP3026

AbMole BioScience

ASP3026

9

1097917-15-1

Chemical

Research Use Only

1

C29H40N8O3S

580.76

ASP3026 is a selective and oral active anaplastic lymphoma kinase (ALK) inhibitor with a IC50 value of 3.5 nM. ASP3026 can inhibit the phosphorylation of IGF-1R, STAT3, AKT and JNK proteins, and induce the cleavage of caspase 3 and PARP. It also inhibited ROS and ACK.

COC1=CC(=CC=C1NC2=NC(=NC=N2)NC3=CC=CC=C3[S](=O)(=O)C(C)C)N4CCC(CC4)N5CCN(C)CC5

12352200