AST-487 (NVP-AST487)

Selleck Chemicals

AST-487 (NVP-AST487) [630124-46-8]

9

Research Use Only

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AST-487 (NVP-AST487), a N,N-diphenyl urea,is an ATP competitive inhibitor of Flt3 with ki of 0.12 microM.Besides FLT3, AST487 also inhibits RET,KDR,c-KIT,and c-ABL kinase with IC50 values below 1 microM.

51202000