Atabecestat

MedChem Express

Atabecestat [1200493-78-2]

10

1200493-78-2

Research Use Only

99.77

C18H14FN5OS

367.40

Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Abeta reduction. Atabecestat s tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat has the potential for Alzheimers Disease treatment [1] .

O=C(C1=NC=C(C#N)C=C1)NC2=CC=C(F)C([C@@]3(C)N=C(N)SC=C3)=C2

-20°C,2°C to 8°C

12352200