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Atabecestat [1200493-78-2]

Atabecestat [1200493-78-2]

Research Use Only
T14338
TargetMol Chemicals
CAS Number1200493-78-2
Product group Chemicals
Estimated Purity99.77%
Molecular Weight367.4
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Overview

  • Supplier
    TargetMol Chemicals
  • Product Name
    Atabecestat [1200493-78-2]
  • Delivery Days Customer
    10
  • CAS Number
    1200493-78-2
  • Category Supplier
    Chemical
  • Certification
    Research Use Only
  • Chemical Name
    Atabecestat
  • Estimated Purity
    99.77%
  • Molecular Formula
    C18H14FN5OS
  • Molecular Weight
    367.4
  • Scientific Description
    Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active beta-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF Abeta reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimers Disease treatment[1].
  • Shelf life instruction
    3 years
  • SMILES
    C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F
  • Storage Instruction
    -20°C
  • UNSPSC
    12352200