Bio-Connect
Western Blot analysis of various samples using ATF1 Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of various samples using ATF1 Polyclonal Antibody at dilution of 1:1000.
Western Blot analysis of various samples using ATF1 Polyclonal Antibody at dilution of 1:1000.

ATF1 Polyclonal Antibody

Research Use Only
E-AB-70146
Elabscience
Product group Antibodies
Sign in to order and to see your custom pricing.
Large volume orders?
Order with a bulk request

Overview

  • Supplier
    Elabscience
  • Product Name
    ATF1 Polyclonal Antibody
  • Delivery Days Customer
    12
  • Certification
    Research Use Only
  • Scientific Description
    This gene encodes an activating transcription factor, which belongs to the ATF subfamily and bZIP (basic-region leucine zipper) family. It influences cellular physiologic processes by regulating the expression of downstream target genes, which are related to growth, survival, and other cellular activities. This protein is phosphorylated at serine 63 in its kinase-inducible domain by serine/threonine kinases, cAMP-dependent protein kinase A, calmodulin-dependent protein kinase I/II, mitogen- and stress-activated protein kinase and cyclin-dependent kinase 3 (cdk-3). Its phosphorylation enhances its transactivation and transcriptional activities, and enhances cell transformation. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma. This gene has a pseudogene on chromosome 6.
  • UNSPSC
    12352203