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ATF3 antibody

GTX129120
GeneTex
ApplicationsImmunoFluorescence, Western Blot, ImmunoCytoChemistry
DownloadDatasheet
Product group Antibodies
TargetATF3
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Overview

  • Supplier
    GeneTex
  • Product Name
    ATF3 antibody
  • Delivery Days Customer
    9
  • Application Supplier Note
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
  • Applications
    ImmunoFluorescence, Western Blot, ImmunoCytoChemistry
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Concentration
    1 mg/ml
  • Conjugate
    Unconjugated
  • Gene ID467
  • Target name
    ATF3
  • Target description
    activating transcription factor 3
  • Target synonyms
    cAMP-dependent transcription factor ATF-3; cyclic AMP-dependent transcription factor ATF-3
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP18847
  • Protein Name
    Cyclic AMP-dependent transcription factor ATF-3
  • Scientific Description
    Activating transcription factor 3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes. [provided by RefSeq]
  • Storage Instruction
    -20°C or -80°C,2°C to 8°C
  • UNSPSC
    12352203

References

  • PFKFB3 modulates glycolytic metabolism and alleviates endoplasmic reticulum stress in human osteoarthritis cartilage. Qu J et al., 2016 Mar, Clin Exp Pharmacol Physiol
    Read more

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Figure 1. Western blotting validation for Anti-ATF-3 Antibody A00904-2 Western Blot (WB) analysis of 293T-UV cells using ATF-3 polyclonal antibody. Electrophoresis was performed on a SDS-PAGE gel. To determine SDS-PAGE gel concentration
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