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ATF6 Antibody, Biotin conjugated

CSB-PA002277LD01HU
Cusabio
ApplicationsELISA
Product group Antibodies
ReactivityHuman
TargetATF6
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Overview

  • Supplier
    Cusabio
  • Product Name
    ATF6 Antibody, Biotin conjugated
  • Delivery Days Customer
    20
  • Applications
    ELISA
  • Certification
    Research Use Only
  • Clonality
    Polyclonal
  • Conjugate
    Biotin
  • Gene ID22926
  • Target name
    ATF6
  • Target description
    activating transcription factor 6
  • Target synonyms
    ACHM7, ATF6A, ATP6alpha, cyclic AMP-dependent transcription factor ATF-6 alpha, cAMP-dependent transcription factor ATF-6 alpha
  • Host
    Rabbit
  • Isotype
    IgG
  • Protein IDP18850
  • Protein Name
    Cyclic AMP-dependent transcription factor ATF-6 alpha
  • Scientific Description
    Transmembrane glycoprotein of the endoplasmic reticulum that functions as a transcription activator and initiates the unfolded protein response (UPR) during endoplasmic reticulum stress. Cleaved upon ER stress, the N-terminal processed cyclic AMP-dependent transcription factor ATF-6 alpha translocates to the nucleus where it activates transcription of genes involved in the UPR. Binds DNA on the 5-CCAC[GA]-3half of the ER stress response element (ERSE) (5-CCAAT-N(9)-CCAC[GA]-3) and of ERSE II (5-ATTGG-N-CCACG-3). Binding to ERSE requires binding of NF-Y to ERSE. Could also be involved in activation of transcription by the serum response factor. May play a role in foveal development and cone function in the retina.
  • Reactivity
    Human
  • Storage Instruction
    -20°C or -80°C
  • UNSPSC
    41116161

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